STABILIZE-CKD

Are you interested in taking part in this clinical study?

We are currently looking for people who have been diagnosed with chronic kidney disease (CKD) to take part in a clinical study called STABILIZE-CKD.

A clinical study is used to help doctors and researchers see if an investigational medicine is safe and works well in humans. Taking part is completely voluntary. The results can help to find better treatments for others in the future.

STABILIZE-CKD will be investigating whether a treatment called sodium zirconium cyclosilicate(SZC), when given alongside a treatment called renin-angiotensin-aldosterone system inhibitor (RAASi), may provide benefit to patients with CKD.

Who can join?

You may be suitable to take part in STABILIZE-CKD if you:

• Have moderate to severe CKD
• Are aged 18 years or over at the time of joining the study
• Have high potassium levels and can benefit from taking RAASi therapy (you may or may not already be taking RAASi therapy)
  OR
• Have normal potassium levels but due to a high risk of these levels rising you are either not undergoing RAASi therapy or undergoing suboptimal RAASi therapy

What will the study involve?
During the study, you will be asked to attend appointments that may include:

• A physical examination, including your height and weight
• Measurements of your vital signs, including temperature, heart rate and blood pressure
• Blood and urine tests
• Electrocardiogram
• Review of your medical history and current medications

You will be asked to attend one follow-up visit at the end of the study.

If you are interested in taking part in the STABILIZE-CKD study, please speak with your doctor for more information.