Did you know, when your blood pressure is too high, even when treated with medication, it can increase your risk of cardiovascular disease?
Find out more about the ZENITH study for people with uncontrolled high blood pressure.
Caring about heart health is important
With almost half of adults worldwide living with high blood pressure, researching potential new treatment options to help lower the risk of cardiovascular disease (CVD) is important. CVD refers to conditions affecting the heart and blood flow.
The ZENITH study aims to find out if an investigational medication, called zilebesiran (pronounced zile-BEE-siran), can help control high blood pressure and lower the risk of cardiovascular events, such as heart attack and stroke. The study will involve:
- Receiving injections of investigational medication or placebo once every 6 months.
- Visiting the study site up to 8 times in the first year, then once every 6 months.
You may* be able to take part if:
- You’re 18 or older,
- you’re taking at least 2 medications for high blood pressure, including a diuretic (water pill)
- AND you have CVD
OR
- You’re 55 or older,
- you’re taking at least 2 medications for high blood pressure, including a diuretic (water pill)
- AND you have a high risk of developing CVD.
Find out more
Visit our website at ZENITHCVstudy.com
*Additional study criteria may apply.

