Learn more about Pfizer’s influenza (flu) vaccine clinical trial.
About this study#
Who can take part
You may qualify to take part in this study if you:
- Are [at least 18] years of age
- Are generally healthy with no major changes in your recent medical history
- Have not tested positive for flu in the last 5 months
- Have not received an approved or investigational flu vaccine in the last 5 months
- Do not have a history of severe allergic reactions associated with any vaccine
There are other requirements that the study team will discuss with you.Study duration
You will be in the clinical trial for about [6 months].
Study visits
You will have at least [3] visits with the study team.
What to expect
If this study is a good fit for you and you agree to take part, you will be assigned by chance (like pulling a number out of a hat) to receive one of the following:
- 1 of 6 different formulations of an investigational mRNA-based vaccine designed to protect against 3 strains of flu, or
- A licensed flu vaccine designed to protect against 3 strains of flu
This study does not include a placebo (injection with no active ingredients).
You will use an electronic diary (eDiary) to track any changes in your health for at least 7 days after receiving your study vaccination.
Volunteering is your choice. You can choose to leave the study at any time, for any reason.
What else to know
- Before you join the clinical trial, you will be given all of the details about participation, including potential benefits and risks. If you would like to participate, you will provide your written consent (permission) before joining the study.
- Safety is always the top priority of any clinical trial. Your health will be carefully monitored throughout the clinical trial by the study team.
- [The study vaccine and study-related procedures will be provided at no cost.] [You will also be [paid for completing study-related activities / reimbursed for some study-related expenses].]
More than 200,000 people in the U.S. are hospitalized with flu every year.1#
Getting vaccinated against flu is an important way to protect yourself and others from serious illness. Since flu viruses are always changing, annual vaccines must be updated as well. mRNA technology has made it easier and faster to produce vaccines that target the most common strains circulating each year.
This study will help us learn if an investigational mRNA-based flu vaccine is safe and can cause an immune response to protect against flu in generally healthy adults [18 years of age and older].
By participating in this study, you will receive an investigational or approved flu vaccine while contributing to research that could help protect others in the future.
Tomorrow’s breakthroughs start today with you
Participation by people of all backgrounds is critical to developing vaccines that protect against flu. Each new vaccine breakthrough helps us reach more people to prevent and reduce the spread of disease.
Thank you for taking the time to learn more.
Ready to learn more?
For more information, contact our study team: 786-772-0510
- Hall E. Influenza. Chapter 12. In: CDC. Hall E, Wodi AP, Hamborsky J, et al, eds. Epidemiology and prevention of vaccine-preventable diseases. 14th ed. Washington, DC: Public Health Foundation; 2021:179-92.
